Originally Posted By: cant_remember

Today, she suggested the possibility of medicating with an opioid antagonist (naloxone or naltrexone), and she gave me an article on it by Ulrich. F. Lanius, which is a chapter from Robin Shapiro's 2005 book EMDR Solutions: Pathways to Healing.

The naloxone (injected) and naltrexone (pill) are typically prescribed for heroin addicts because it blocks heroin's ability to bond with the brain. But apparently it can also prevent dissociation?

I'm just wondering if anyone else has heard about this or tried it. My T and I are going to have to work out details because she can't administer an injection of naloxone, so might have to meet her at a psychiatrist's office or something.


I came across naloxone in a book I'm reading on healing from abuse. The book is: Psychological Trauma and the Developing Brain. Neurologically based interventions for troubled children by Phyllis T. Stien and Joshua Kendall. The context of the mention is the use of specific drugs to help alter brain chemistry to aid in recovery from abuse. New types of drugs are being introduced in the treatment of PTSD, including CRF antagonists, neuropeptide Y enhancers, drugs to downregulate cortisol receptors, anticonvulsants and anti-adrenergic agents. Furthermore, drugs that block the effects of opiods can be effective in inhibiting dissociative symptoms. The naloxone is discussed in chapter 5, page 138:



Bruce Perry (a psychiatrist) tells the story about being summoned to the emergency room to treat a traumatized adolescent girl who was in a catatonic state. After an injection of naloxone, she woke up and was able to respond normally.

I have found this book to be excellent because it seems to discuss all the varied symptoms I had as a child (and still had as an adult). The book gives treatment (therapy) processes. The book is NOT bedside reading. It is a little bit technical.