I receive it as new medicine on Friday, for an arthritis. It is in a vein, at office of the doctor, more than hour, they inserted it. It will be possible well as only I receive it each 2 months. But as Friday, was very sick in my stomach and vomit very much. It seems, that it becomes better the some now, so possible, that is finished. I only specified by a question if who - or still, they ever takes this medicine if they have problems of it? Thanks.